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October 16, 2009
The effect of a plant-based low-carbohydrate ("Eco-Atkins") diet on body weight and blood lipid concentrations in hyperlipidemic subjects. Arch Intern Med 2009;169:1046-54
Jenkins DJ, Wong JM, Kendall CW, Esfahani A, Ng VW, Leong TC, Faulkner DA, Vidgen E, Greaves KA, Paul G, Singer W.

Description of this Publication

The effects of a low-carbohydrate, high-vegetable protein and vegetable oil plant-based diet and of a high-carbohydrate lacto-ovo vegetarian diet for 4 weeks on the lipoprotein-lipid profile were compared in a sample of 47 overweight hyperlipidemic men and women. Although weight loss was similar between the two groups, reductions in LDL cholesterol, triglycerides, the cholesterol/HDL cholesterol ratio and the apolipoprotein B/apolipoprotein AI ratio were greater for the low-carbohydrate compared to the high-carbohydrate diet. A significantly greater decrease in systolic and diastolic blood pressure was observed for the low-carbohydrate vs. the high-carbohydrate diet. Thus, a plant-based low-carbohydrate diet high in vegetable proteins and oils may be efficient in treating dyslipidemic subjects for whom weight loss and a reduction in LDL cholesterol concentrations are needed.

Although the paper of Jenkins et al. provided some evidence that a high vegetable protein diet could be effective and safe for weight loss and improving cardiovascular risk factors, Tuttle and Milton in their editorial (Arch Intern Med 2009; 169: 1027) believe that it is still premature to recommend the “Eco-Atkins” diet until more data are available to prove its efficacy in larger populations and higher-risk individuals.


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Key Words
Nutrition, Lipids/Lipoproteins, Obesity