Evaluating CMR

Assessing CVD Risk: Traditional Approaches

Framingham

Key Points

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  • The seminal Framingham Heart Study has helped identify many major CHD risk factors by providing a simple CHD prediction algorithm that uses categorical variables to help physicians evaluate their patients’ CHD risk.
  • The Framingham risk score is a useful tool to predict the absolute CHD risk of men and women who are initially free of CHD.
  • Some of the most significant milestones of the Framingham study include the following:

1960: Cigarette smoking found to increase CHD risk
1961: Cholesterol levels, blood pressure, and electrocardiogram abnormalities found to 
          increase the risk of heart disease
1967: Physical activity found to reduce the risk of CHD and obesity to increase
          the risk of CHD
1977: High HDL cholesterol levels found to protect against CHD
1981: Low LDL cholesterol concentrations linked to low incidence of CHD