Metabolic Syndrome and Type 2 Diabetes/CVD Risk
- 1Key Points (1 page)
- 2WHO Definition and Criteria (2 pages)
- 3EGIR Definition and Criteria (2 pages)
- 4AACE (3 pages)
- 5References (1 page)
- WHO was the first major organization to produce a definition of the metabolic syndrome that focused mainly on insulin resistance, whose diagnosis requires an oral glucose tolerance test.
- WHO criteria also proposed that microalbuminuria as a marker to identify high-risk patients with the metabolic syndrome.
- In response to WHO, EGIR sought to establish criteria that would be easier to use in clinical practice. EGIR makes measuring insulin resistance mandatory.
- The AACE position does not provide a specific scoring system for diagnosing the “insulin resistance syndrome”. Insulin resistance is at the core of AACE criteria, while waist circumference is not considered a diagnosis criterion.
- These organizations acknowledge that their diagnosis tools can be refined and that further research is needed to improve diagnosis of the metabolic syndrome in clinical practice.