The Concept of CMR
Slides, videos and moreEvaluating CMR
Metabolic Syndrome and Type 2 Diabetes/CVD Risk
Usefulness of Hypertriglyceridemic Waist
- 1Key Points (1 page)
- 2History of Hypertriglyceridemic Waist (3 pages)
- 3Prevalence of Hypertriglyceridemic Waist (1 page)
- 4Hypertriglyceridemic Waist and Coronary Risk (3 pages)
- 5Hypertriglyceridemic Waist and Diabetes (1 page)
- 6Hypertriglyceridemic Waist Predicts Metabolic Abnormalities (1 page)
- 7Hypertriglyceridemic Waist and Global CHD Risk (1 page)
- 8References (1 page)
Hypertriglyceridemic Waist and Coronary Risk
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These criteria alone were not as effective as hypertriglyceridemic waist in predicting the annual progression rate of aortic calcification. In a recent 7.5 year prospective study (the SU.VI.MAX study) of 3,430 middle-aged men, using subjects with low waist girth and low triglyceride concentrations as the reference group, investigators reported that the risk of developing CVD over the follow-up only increased significantly among men with hypertriglyceridemic waist after adjusting for age, active smoking, physical activity, systolic blood pressure, diastolic blood pressure, and fasting blood glucose (relative risk: 2.13, 95% CI: 1.21-3.76) (16).
Although it has been reported that hyperglycemia (even in the nondiabetic range) increases CAD (26, 27), it is not clear whether it is dysglycemia that has a direct impact on CAD risk or the metabolic syndrome frequently observed among dysglycemic patients. This question has been examined, and the results showed that the presence/absence of hypertriglyceridemic waist modulated hyperglycemia-related CAD risk in men (14). For instance, in the absence of hypertriglyceridemic waist, men with fasting hyperglycemia (in isolation) were not at increased risk of CAD. However, the CAD risk associated with hypertriglyceridemic waist significantly increased in both men with normal glucose levels (<6.1 mmol/l) or with an impaired fasting glucose concentration (6.1-6.9 mmol/l). An investigation of a large sample of men and women from the Hoorn study confirmed these results.
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