Evaluating CMR

Metabolic Syndrome and Type 2 Diabetes/CVD Risk

Usefulness of Hypertriglyceridemic Waist

Hypertriglyceridemic Waist and Diabetes

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Hypertriglyceridemic waist has also been shown to be associated with increased type 2 diabetes rates in adult men and women (10, 18). Using data from NHANES III, both men and women aged 40 to 74 with hypertriglyceridemic waist were found to have an estimated diabetes prevalence of 25.4%, with this prevalence being only 8.0% in subjects without this phenotype (relative risk: 3.2: 95% CI: 2.4-4.0) (18). The odds of developing diabetes was also markedly higher in men of the Québec Health Survey with an elevated waist circumference and high triglyceride concentration (10). A twelvefold increase in the prevalent odds ratio of diabetes (95% CI: 5.1-27.9, p<0.0001) was observed in men with hypertriglyceridemic waist compared to the reference group of men with both low waist girth and triglyceride levels. The prevalent odds ratio was not as high among obese (body mass index (BMI) ≥ 30 kg/m2) versus normal weight men (odds ratio: 7; 95% CI: 3.4-13.9, p<0.0001). Furthermore, the metabolic profile of men with hypertriglyceridemic waist was as worse as, if not worse than, that of men with diabetes (10).


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10. Lemieux I, Alméras N, Mauriège P, et al. Prevalence of "hypertriglyceridemic waist" in men who participated in the Quebec Health Survey: association with atherogenic and diabetogenic metabolic risk factors. Can J Cardiol 2002; 18: 725-32.
18. Kahn HS and Valdez R. Metabolic risks identified by the combination of enlarged waist and elevated triacylglycerol concentration. Am J Clin Nutr 2003; 78: 928-34.