The Concept of CMR
Slides, videos and moreManaging CMR
Managing Cardiometabolic Risk in Abdominally Obese Patients
Physical Activity and Exercise
- 1Key Points (1 page)
- 2Exercise and Cardiometabolic Risk (2 pages)
- 3Exercise and Abdominal Obesity (3 pages)
- 4Exercise and Insulin Resistance (5 pages)
- 5Exercise and Atherogenic Dyslipidemia (4 pages)
- 6Exercise and Elevated Blood Pressure (3 pages)
- 7Exercise and Thrombosis (3 pages)
- 8Exercise and Systemic Inflammation (3 pages)
- 9References (1 page)
Exercise and Insulin Resistance
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Insulin resistance has traditionally been cited as the common soil for development of both type 2 diabetes and CVD, and it has been regarded as a key component of cardiometabolic risk (2, 32). The role of insulin resistance in the development of impaired glucose tolerance and overt type 2 diabetes is well established (33, 34). Fortunately, both an acute exercise bout and/or chronic aerobic exercise training have been shown to significantly improve insulin sensitivity and thereby reduce risk of diabetes (35).
Reference
2.
Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-607.
32.
DeFronzo RA. Insulin resistance, hyperinsulinemia, and coronary artery disease: a complex metabolic web. J Cardiovasc Pharmacol 1992; 20 Suppl 11: S1-16.
33.
DeFronzo RA, Bonadonna RC and Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 1992; 15: 318-68.
34.
Lillioja S, Mott DM, Spraul M, et al. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med 1993; 329: 1988-92.
35.
Henriksen EJ. Invited review: Effects of acute exercise and exercise training on insulin resistance. J Appl Physiol 2002; 93: 788-96.
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