The Concept of CMR

Epidemiology

CVD risk and Type 2 Diabetes: Beyond Hyperglycemia

Key Points

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  • Type 2 diabetes is a significant CVD risk factor. However, the independent contribution of hyperglycemia per se to CVD risk remains uncertain.
  • The hyperglycemic state of diabetes is only one of the dysmetabolic components observed in patients, who are often abdominally obese.
  • The cluster of atherogenic metabolic abnormalities now often referred to as the metabolic syndrome is known to increase the risk of type 2 diabetes and CVD.
  • Intervention trials have shown that reducing body weight in overweight and obese subjects at high risk of developing diabetes could substantially reduce their risk of developing diabetes.
  • Age is also an important factor to consider when evaluating the CVD risk of diabetic patients.