The Concept of CMR

Epidemiology

Type 2 Diabetes

More and more people are developing diabetes worldwide, and the most common form of diabetes (over 97% of all cases) is type 2 diabetes. A high percentage of patients (65 to 80%) with type 2 diabetes will die from cardiovascular disease (CVD). Although mortality from CVD has been declining in some countries, such has not been the case for diabetic patients. Overall, the absolute risk of coronary heart disease death is roughly three times higher in diabetic patients than in non-diabetic patients. In diabetic patients, heart disease manifests as macrovascular and microvascular complications as well as a series of metabolic abnormalities such as impaired plasma glucose-insulin homeostasis. In this regard, although elevated fasting blood glucose is strongly indicative of type 2 diabetes risk, it plays a lesser role in predicting CVD risk. Evidence available suggests that the clustering risk factors observed in type 2 diabetic patients largely account for their high rates of cardiovascular morbidity and mortality.