The Concept of CMR

Intra-abdominal Adipose Tissue: the Culprit?

Gender Differences

Key Points

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There is a definite gender difference in adipose tissue distribution:

  • Men accumulate adipose tissue in the intra-abdominal cavity (apple pattern).
  • Women accumulate adipose tissue in the gluteal/femoral depots (pear pattern).
  • Intra-abdominal adipose tissue accumulation—the adipose tissue distribution pattern generally found in men—predicts greater obesity-related health risks.
  • Pre-menopausal women have less intra-abdominal adipose tissue and a more favourable metabolic risk profile than men with similar total body fat. This protection against intra-abdominal (visceral) fat accumulation is lost when women enter menopause.