The Concept of CMR
Intra-abdominal Adipose Tissue: the Culprit?
Gender Differences
- 1Key Points (1 page)
- 2A Question of Gender: Apples and Pears… (3 pages)
- 3Metabolic Consequences of Gender Differences in Regional Adipose Tissue Distribution (2 pages)
- 4References (1 page)
Key Points
There is a definite gender difference in adipose tissue distribution:
- Men accumulate adipose tissue in the intra-abdominal cavity (apple pattern).
- Women accumulate adipose tissue in the gluteal/femoral depots (pear pattern).
- Intra-abdominal adipose tissue accumulation—the adipose tissue distribution pattern generally found in men—predicts greater obesity-related health risks.
- Pre-menopausal women have less intra-abdominal adipose tissue and a more favourable metabolic risk profile than men with similar total body fat. This protection against intra-abdominal (visceral) fat accumulation is lost when women enter menopause.

The Concept of CMR
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